Which statement best describes the biological response of tissue to calcium hydroxide?

The correct choice highlights the role of calcium hydroxide in dental tissue response, particularly its ability to stimulate the formation of secondary dentin. Calcium hydroxide is known for its bioactive properties, and when applied to the dental pulp or other dental tissues, it promotes the deposition of secondary dentin as a response to irritation or injury. This is beneficial in scenarios such as pulp capping or treating deep carious lesions, where protecting the pulp and allowing for healing is a priority.

The formation of secondary dentin acts as a natural barrier, reinforcing tooth structure and preserving vitality in cases where the pulp may be at risk. This regenerative aspect is crucial in restorative dentistry, making calcium hydroxide a common choice in procedures aimed at preserving pulp health.

Other options may refer to different characteristics of calcium hydroxide, such as its irritant nature or potential analgesic properties, but these do not capture the primary beneficial biological response related to tissue in a restorative context as effectively as the formation of secondary dentin does.